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pharmacogenomics in primary care

Pharmacogenomics in Primary Care

Explain one of the following statements in your own words. Give an example of implications for you as the prescribing primary care provider.

  1. Carbamazepine has a black box warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy.
  2. Testing for CYP2D6 variants prior to starting tamoxifen for breast cancer.
  3. A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is inactivated by the body.

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